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Everyday Essentials | Knowledge from The Edge #10 Chemistry – Penicillin

Common Question: What is the mode of action of Penicillin in combating infectious disease?
Answer: The “beta lactam” ring in Penicillin breaks in-vivo and cross-links to a serine amino acid in penicillin binding proteins (PBPs), thereby preventing the polymer peptidoglycan forming the cell wall in bacterium cells.


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